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Research
Gerard Grosveld, PhD
The Department of Genetics studies the genetic and molecular basis of several human diseases; molecular mechanisms involved in early mouse development and organogenesis; molecular mechanisms involved in metabolic disorders; DNA damage responses in the central nervous system; and the roles of oncogenes, tumor suppressors, and signaling pathways in cancer.
A central theme in the department is the use of mouse models to study gene function and to test gene and small molecule therapeutic strategies for cancer and metabolic diseases. Engineered animals are generated in the Transgenic/Gene Knock-out Facility, which is maintained by the department.
Genetics
MS 331, Room D3055
St. Jude Children's Research Hospital
262 Danny Thomas Place
Memphis, TN 38105-3678
Email: gerard.grosveld@stjude.org
Telephone: 901-595-2692
Fax 901-595-6035
Preferred contact method: email
Alessandra d'Azzo, PhD Intracellular degradation in development & disease
Gerard Grosveld, PhD The role of chromosome translocations in cancer
Peter J. McKinnon, PhD DNA damage signaling and disease
Guillermo Oliver, PhD Development of the CNS/visual system and lymphatic vasculature
Beatriz Sosa-Pineda, PhD Pancreas and liver organogenesis in mammals
